Dna platination
WebImportance of DNA Sequence in the Reaction of d(ApG) and d(GpA) with Cis-Diamminedichloroplatinum (II).- Changes in UV-Absorbance are Due to Slow and Fast Conformational Rearrangements during DNA-Platination.- Visualization of Cisplatin-DNA and Carboplatin-DNA Adducts in Tissues and Cultured Cells.- WebJun 25, 2024 · A heptamethine cyanine scaffolded Pt II complex, IR797-Platin exhibits unprecedented Pt−O bond scission and enhancement in DNA platination in near-IR …
Dna platination
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WebKinetics of small molecules with RNA and DNA using analytical techniques. Analysis of impact of platination on glycosidic bond stability of nucleic acid residues. Selective … WebDesign of polyfunctional probes for the detection and capture of nucleic acids secondary structures, G-quadruplex DNA, and associated proteins. - Management of several long-term research projects ... Subsequently the capacity of the compounds to establish one or two anchorage points (one by platination, one by photoinduced crosslinking) ...
WebThe main changes were observed between the B-DNA native conformation and either Z-DNA or A-DNA, with a higher effect on lipids having been detected in the presence of … Platinum(II) acetylacetonate (97%), oleylamine (80–90%), lithium triethylborohydride, N-Hydroxysuccinimide sodium salt (NHS), N-(3-Dimethylaminopropyl)-N’-ethylcarbodiimide hydrochloride (EDC), cysteamine (CA), tetrahydrofuran (THF), N,N-dimethylformamide (DMF), 2-(N … See more Transmission electron microscopy (TEM) analysis was performed on a transmission electron microscope (Hitachi HT7700, Japan). High-resolution transmission electron microscopy … See more Pt nanoclusters (PtNCs) of ~2.5 nm in diameter were synthesized via the thermal decomposition method. In a typical process, 0.4 g of Platinum(II) acetylacetonate and … See more The Pt ion release behaviour of NMPNs after the discharge of mPEG5K-AC-CA at different time points (0.5, 2, 4, 8 h) was analyzed by using ICP-MS. First, NMPNs were treated with PBS (pH 6.5) for 6 h. Then, PBS (pH 6.5) … See more One gram of mPEG5K-OH (Mw = 5000) was dissolved in 15 mL of Ar-purged tetrahydrofuran (THF) under ice-water bath. Then, 460 μL of TEA and 200 μL of acryloyl chloride were slowly injected into the mixture. The … See more
WebDNA DNA-Binding Proteins DNA, Viral DNA, Bacterial RNA, Messenger Oligodeoxyribonucleotides DNA Restriction Enzymes RNA, Viral Transcription Factors DNA Primers Recombinant Fusion Proteins Deoxyribonuclease I Deoxyribonucleases, Type II Site-Specific Nylons Oligonucleotides Viral Proteins Oligonucleotide Probes RNA … WebDesign of polyfunctional probes for the detection and capture of nucleic acids secondary structures, G-quadruplex DNA, and associated proteins. - Management of several long …
WebApr 9, 2024 · Cellular trafficking, accumulation and DNA platination of a series of cisplatin-based dicarboxylato ... Platinum and other metal coordination compounds in cancer chemotherapy : proceedings of the Fifth In... Antitumor complexes of platinum with carrier molecules. 3. Cytotoxicity of some platinum amino acid ...
WebWe also directly observed that the degree of platination of DNA strongly depends on the concentration of sodium chloride as required for cisplatin's intracellular activity. Our study shows that micromanipulation techniques accurately reveal the degree of chemical modification of DNA which can be used for a new type of structure-sensitive ... chambering a championship match barrelWebMar 2, 2024 · In order to develop a novel platinum (Pt) complex aiming to overcome cisplatin resistance, we synthesised a series of novel Pt complexes (C1–C6).These Pt complexes … happy new year in mexicoWebNov 12, 2024 · The authors demonstrated that the complexes exhibit strong DNA-binding affinity via intercalation with binding constants in the range 0.30 × 10 5 –6.25 × 10 5 L/mol. Intriguingly, ... It is evident from these presented examples that platination may be an ingenious strategy to augment the efficacy of antimalarial agents, ... chambering borangWebSep 21, 2024 · Furthermore, repression of specific DNA repair genes was restricted to oxaliplatin. Transcriptional level observations were further analyzed on the functional … happy new year in michifWebBiosensors based on DNA self-assembled monolayers (DNA-SAMs) combined with electrochemical transducers have shown great potential to serve an important role in simple, accurate and inexpensive genetic analysis relevant to many fields. Recently we have reported on observing a significant change in the viscoelasticity of such DNA layers … chambering kjvWebDownloadable! Platinum (Pt) resistance in cancer almost inevitably occurs during clinical Pt-based chemotherapy. The spontaneous nucleotide-excision repair of cancer cells is a … happy new year in native american languagesWebHomo-DNA is an oligonucleotide homologue based ondideoxy-hexopyranosyl sugar moieties, ... The significant alteration of fragmentation due to platination is demonstrated by comparison of the fragment ion patterns of unplatinated and platinated 2′-O-methyl- and 2′-O-methyl methylphosphonate oligoribonucleotides, ... chambering a remington 700 barrel