Hyperinfectivity
Web1 jun. 2010 · A wide variety of genes have been identified that are upregulated in a biofilm and thus could participate in biofilm-induced hyperinfectivity (42, 52, 61, 62). We selected 10 genes covering a variety of putative functions, as listed in Table Table2, 2, for mutagenesis and examined the mutants for loss of hyperinfectivity. Web5 mrt. 2024 · We formulate the model by a reaction–diffusion system with space-dependent parameters and bacterial hyperinfectivity, where susceptible and infectious humans …
Hyperinfectivity
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Web20 apr. 2024 · A new study led by researchers at UC Santa Cruz goes a long way toward explaining the hyperinfectivity of cholera biofilms. The study, published the week of April 20 in the Proceedings of the National Academy of Sciences (PNAS), is one of several new papers on cholera biofilms from the laboratory of UCSC microbiologist Fitnat Yildiz. Web1(x;t) (hyperinfectious (HI)) and V. 2(x;t) (lower-infectious (LI)) vibrios to measure the infectivity of vibrios, where xand t are spatial and time variables, respectively. Recent …
WebSpatio-temporal dynamics of an age-space structured cholera model with bacterial hyperinfectivity and imperfect vaccination Rui Xu 1,2, , and Ning Bai 1,2,3, 1. Complex Systems Research Center, Shanxi University, Taiyuan, 030006, Shanxi, China 2. Shanxi Key Laboratory of Mathematical Techniques and Big Data Analysis, on ... Web1 jan. 2024 · In this paper, we are concerned with the mathematical analysis of a host–pathogen model with diffusion, hyperinfectivity and nonlinear incidence. We define the basic reproduction number ℜ 0 by the spectral radius of the next generation operator, and study the relation between ℜ 0 and the principal eigenvalue of the problem …
Web27 jun. 2006 · Citation: Pascual M, Koelle K, Dobson AP (2006) Hyperinfectivity in cholera: A new mechanism for an old epidemiological model? PLoS Med 3(6): e280. DOI: 10.1371/journal.pmed.0030280 Funding: The authors acknowledge the joint support by the National Science Foundation–National Institutes of Health (Ecology of Infectious … Web6 jun. 2024 · A model of cholera transmission with hyperinfectivity and its optimal vaccination control. Chairat Modnak; Chairat Modnak. Department of Mathematics, Faculty of Science, Naresuan University, Phitsanulok 65000, Thailand. E-mail Address: [email protected] Search for more papers by this author
WebDownloadable (with restrictions)! In this paper, we are concerned with the mathematical analysis of a host–pathogen model with diffusion, hyperinfectivity and nonlinear incidence. We define the basic reproduction number ℜ0 by the spectral radius of the next generation operator, and study the relation between ℜ0 and the principal eigenvalue of the problem …
Web15 dec. 2024 · To our knowledge, few works have taken spatial heterogeneity and bacterial hyperinfectivity into consideration simultaneously, although these two factors and … eric cortina seating depthWebV. cholerae biofilms have been shown to be hyperinfective, but the mechanism of hyperinfectivity is unclear. Here we show that biofilm-grown cells, irrespective of the surfaces on which they are formed, are able to markedly outcompete planktonic-grown cells in the infant mouse. Using an imaging technique designed to render intestinal tissue ... find nissanWeb30 apr. 2024 · Upregulation of virulence genes promotes Vibrio cholerae biofilm hyperinfectivity. Gallego-Hernandez AL, DePas WH, Park JH, Teschler JK, Hartmann R, Jeckel H, Drescher K, Beyhan S, Newman DK, Yildiz FH. PMID: 32355001. Abstract eric cortina shootingWeb6 dec. 2005 · If indeed such a state exists, this hyperinfectivity is key to understanding the explosive nature of human-to-human transmission in outbreaks. Contact with freshly … find nintendo switch playersWeb31 jan. 2024 · In this paper, we are concerned with the threshold dynamics of a diffusive cholera model incorporating latency and bacterial hyperinfectivity. Our model takes the … eric corti net worthWeb1 feb. 2006 · Cholera, caused by the bacterium Vibrio cholerae, is an acute intestinal disease that can be transmitted to humans through indirect contact with the … eric corwinWebThese findings help to substantiate the clinical relevance of laboratory observations regarding the hyperinfectious state, and underscore the critical importance of human-to-human versus environment-to-human transmission in the generation of epidemic and pandemic disease.ConclusionsTo have maximal impact on limiting epidemic spread of … find ni number free