Webedoxaban + fluvoxamine use alternative or monitor bleeding s/sx: combo may incr. edoxaban levels, risk of bleeding (incl. life-threatening ... edoxaban + phenytoin avoid … WebThe specific recommendations are based on indication, renal function, and effect of the co-administered P-gp inhibitors on the concentration of dabigatran or edoxaban. Clinical monitoring is recommended when a DOAC not affected by CYP3A4 but transported by P-gp, including dabigatran etexilate and edoxaban, is co-administered with PREZCOBIX.

edoxaban oral and phenytoin oral Drug Interactions - RxList

WebNational Center for Biotechnology Information WebDirect oral anticoagulants are mainly affected by medications strongly affecting the permeability glycoprotein (P-gp), and to a lesser extent, strong CYP3A4 … the tox corporation

Information sheet for Enoxaparin for Primary Care Prescribers

WebAlthough edoxaban undergoes minimal hepatic metabolism via the cytochrome P450 (CYP) system, edoxaban should not be used in conjunction with strong CYP3A4 and P … WebIn recent years, warfarin's competition, direct oral anticoagulants (DOACs), has seen a rise in demand. Oral anticoagulants known as DOACs are those that directly block the coagulation factors, either thrombin (in the case of dabigatran) … Web• phenytoin • prazocin • rifampin • St. John’s Wort • tenofovir • tipranavir • trazodone • vinblastine Strong inducers of CYP3A4 • bosentan • efavirenz • etravirine • fosphenytoin • … seventeen diamond edge pics